PYRROLE DISORDER

Other Terms: Pyroluria

Background:

Pyrrole disorder is characterized by an inborn genetic disorder in pyrrole chemistry causing an excess of kryptopyrrole molecules. Kryptopyrrole is a byproduct of hemoglobin synthesis. It binds with Vitamin B6 and with available zinc, thus causing a depletion of both. Zinc and Vitamin B6 are essential in supporting neurotransmitters. Elevated urinary pyrroles is a good biomarker for oxidative stress.

Manifestations and Symptoms:

• Labile emotions, often described as "Jekyll & Hyde" personality
• Low stress tolerance
• May have sensitivity to light, sound, touch, and texture of food or clothing (tags, elastic or material)
• Fears or phobias
• Easily fatigued, irritated, or overwhelmed
• Poor dream recall
• Poor appetite in the morning (may be prone to AM nausea or motion sickness)
• Light complexion and hair color compared to others in family
• Sunburns easily, may itch in the sun
• May complain of a "stitch in side"
• Premature graying of hair
• Skin concerns (e.g., acne, stretch marks, eczema, psoriasis, cold sores)
• Soft, brittle nails
• Prone to misperceptions and amnesia

Conditions Which Worsen Pyrrole Disorder :

• Stress (emotional or physical)
• Hormone fluctuation associated with puberty, menstruation, pregnancy, post-partum, menopause and andropause
• Illness

Other Diagnoses Seen in Patients with Pyrrole Disorder:

• Depresssion
• ADD/ADHD
• Autism
• Learning Disorder
• Schizophrenia
• Bipolar Disorder
• Poor Anger Management
• Oppositional Defiant Disorder (ODD)
• Premenstrual Syndrome (PMS) or Premenstrual Dysphoric Disorder (PMDD)

Diagnoses and Treatment:

Urine testing to measure the kryptole molecules along with a full evaluation by our medical doctor determines the diagnosis of pyrrole disorder.

Targeted, advanced individualized nutrient program is prescribed dependent on diagnostic findings.